Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

MG780: Molecular Glue In Vitro Ubiquitination Assay Kit

LifeSensors MG780 Molecular Glue Evaluation Kit: Assess efficacy in protein degradation and drug discovery research.

$1,045.00

Proteolysis Targeting Chimeras (PROTACs) have emerged as novel therapeutics to target the undruggable proteome. Molecular Glues are naturally occurring molecules that bind an E3 and a target. This subsequently leads to ubiquitination and degradation of the target protein. The In vitro ubiquitination kit has been developed to establish a high throughput approach that can accurately predict Molecular Glue efficiency by monitoring the protein’s intrinsic ability to get ubiquitinated. Molecular Glue In Vitro Ubiquitination Assay Kit Components
In Vitro ubiquitination Assay Plate 1 plate
Assay Buffer (10X) 1.2mL
E3 Mix (20X) 1 X 250µL
E1-E2-Ubiquitination Mix (20X) 1 X 250µL
Secondary Antibody (Anti-Mouse or Anti-Rabbit HRP conjugate) 60µL (100X)
Detection Reagent 1Detection Reagent 2 DR1L- 1mLDR2L- 1mL
Blocking Concentrate (5X) 5mL
Molecular Glue in DMSO (50X) 10µL
Target Protein positive control CK1α (20X) 20µL
Anti-CK1α Antibody (100X) 5µL
Anti-mouse HRP Conjugate (100X) 5µL

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

Available Monday – Friday, 9:00 AM – 5:00 PM EST
We typically respond within 24 hours

Visit Anytime

271 Great Valley Parkway Malvern, PA 19355

Send us a Message

Have a question about our solutions? We’d love to hear from you.
* Required fields

More from This Category

LifeSensors' Phospho(Ser65)-Ubiquitin Mutant Biotinylated is a high-purity, biotinylated, phosphorylated ubiquitin for advanced PINK1/Parkin pathway research....
LifeSensors DB999 is a specialized tool for ubiquitin proteasome research, enabling precise detection and analysis of ubiquitin and ubiquitin-like modifications....
LifeSensors UM406M is an M1 Linear Ubiquitin TUBE (Magnetic) for sensitive detection, isolation, and characterization of polyubiquitylated proteins in cells....
LifeSensors UM602 TUBE 2 FLAG is a high-affinity tandem ubiquitin binding entity for selective enrichment of polyubiquitinated proteins, enhancing proteomics....

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Menu

Learning Center