Questions about a product, technology or experimental design? Give us a call 610-644-8845.

MG780: Molecular Glue In Vitro Ubiquitination Assay Kit

LifeSensors MG780 Molecular Glue Evaluation Kit: Assess efficacy in protein degradation and drug discovery research.

$1,045.00

Proteolysis Targeting Chimeras (PROTACs) have emerged as novel therapeutics to target the undruggable proteome. Molecular Glues are naturally occurring molecules that bind an E3 and a target. This subsequently leads to ubiquitination and degradation of the target protein. The In vitro ubiquitination kit has been developed to establish a high throughput approach that can accurately predict Molecular Glue efficiency by monitoring the protein’s intrinsic ability to get ubiquitinated. Molecular Glue In Vitro Ubiquitination Assay Kit Components
In Vitro ubiquitination Assay Plate 1 plate
Assay Buffer (10X) 1.2mL
E3 Mix (20X) 1 X 250µL
E1-E2-Ubiquitination Mix (20X) 1 X 250µL
Secondary Antibody (Anti-Mouse or Anti-Rabbit HRP conjugate) 60µL (100X)
Detection Reagent 1Detection Reagent 2 DR1L- 1mLDR2L- 1mL
Blocking Concentrate (5X) 5mL
Molecular Glue in DMSO (50X) 10µL
Target Protein positive control CK1α (20X) 20µL
Anti-CK1α Antibody (100X) 5µL
Anti-mouse HRP Conjugate (100X) 5µL

send us a message for pricing

CONTACT INFORMATION

Phone (Office)

610.644.8845

SEND EMAIL

info@lifesensors.com

VISIT ANYTIME

271 Great Valley Parkway Malvern, PA 19355

More from This Category

PROTAC IS A REGISTERED TRADEMARK OF ARVINAS OPERATIONS, INC., AND IS USED UNDER LICENSE.