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Unraveling Chain specific Ubiquitination in Cells Using Tandem Ubiquitin Binding Entities in a High Throughput Assay
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LifeSensors Inc. Receives $5.53 Million Funds from National Institutes of Health to Develop PROTAC Drug Discovery and Diagnosis of Alzheimer’s Disease
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HTS Screening of Poly-Ubiquitin Linkage-Specific Molecular Glues and Protein Degraders
Targeting K-RAS Molecular Glues: Kidnapping a New Ligase to Discover Novel Degraders
Accelerating PROTAC drug discovery: Establishing a relationship between ubiquitination and target protein degradation
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TUBEs work in Plants!
HTS Screening of Poly-Ubiquitin Linkage-Specific Molecular Glues and Protein Degraders
Targeting K-RAS Molecular Glues: Kidnapping a New Ligase to Discover Novel Degraders
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Ubiquitin Chains
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SI6304B: Biotinylated K63-Linked Tetra-Ubiquitin
SI-6304B-0025
Biotinylated Ubiquitin Chains
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Ubiquitin and Neuro-degeneration
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Ubiquitin Chains
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Ubiquitin Chains and Derivatives
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UB323: Parkin C457S Mutant E3 Ligase
UB-0323-0025
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SI0604BP: Biotinylated K6-Linked Tetra-Ubiquitin (Phosphorylated)
SI-0604BP-0025
Biotinylated Ubiquitin Chains
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Ubiquitin Chains and Derivatives
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SI1104BP: Biotinylated K11-Linked Tetra-Ubiquitin (Phosphorylated)
SI-1104BP-0025
Biotinylated Ubiquitin Chains
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SI1104B: Biotinylated K11-Linked Tetra-Ubiquitin
SI-1104B-0025
Biotinylated Ubiquitin Chains
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Ubiquitin and Neuro-degeneration
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Ubiquitin Chains
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Ubiquitin Derivatives
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SI3304BP: Biotinylated K33-Linked Tetra-Ubiquitin (Phosphorylated)
SI-3304BP-0025
Biotinylated Ubiquitin Chains
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Phosphorylated Ubiquitin Chains
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Ubiquitin and Neuro-degeneration
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Ubiquitin Chains
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Ubiquitin Chains and Derivatives
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Ubiquitin Derivatives
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SI3304B: Biotinylated K33-Linked Tetra-Ubiquitin
SI-3304B-0025
Biotinylated Ubiquitin Chains
,
Ubiquitin and Neuro-degeneration
,
Ubiquitin Chains
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Ubiquitin Chains and Derivatives
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Ubiquitin Derivatives
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SI0104P: M1 (linear) Tetra-Ubiquitin (Phosphorylated)
SI-0104P-0025
Ubiquitin and Neuro-degeneration
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Ubiquitin Chains
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SI4803P: K48-Linked Tri-Ubiquitin (Phosphorylated)
SI-4803P-0025
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SI4802P: K48-Linked Di-Ubiquitin (Phosphorylated)
SI-4802P-0025
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Ligase and Substrate Screening
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BioPROTACs - MRNA Chimeras
Antibody Mediated Degradation
Exracellular Targeted Protein Degradation
Ubiquitin and Ubiquitin Chains
Ubiquitin Chains for DUB Screening
Biotinylated Ubiquitin Chains
Ubiquitin K to R mutants
SUMO Technology & Protein Expression
Polypeptide Manufacturing
Therapeutic Proteins, Dramatic Enhancement
Nanobodies and Single Chain Antibodies
Vaccine Manufacturing with SUMO
Gene Therapy: SUMO to the rescue
Neurodegeneration
Dysfunction of the Ubiquitin Proteasome System
Phospho-Ubiquitin as a Biomarker
Parkinsons Disease
Alzheimer’s Disease
Tandem Ubiquitin Binding Entities (TUBEs)
Molecular Glue Degraders
PROTAC and DUBTAC Drug Discovery
Ubiquitin and Ubiquitin Chains
SUMO Technology & Protein Expression
Neurodegeneration
Phospho-Ubiquitin as a Biomarker
Alzheimer’s Disease
R&D Services
PROTAC & Molecular Glues
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Target Exploration and Validation
Novel E3 Ligases For PROTAC
PROTAC Ternary Complex Formation Assays
PROTAC for Cancer
PROTAC for Neuroscience
SUMO-Fusion Protein Expression & Purification
Bacterial
SUMOpro E. Coli
SUMOstar
Advanced Therapeutic Applications
SUMOstar Mammalian
Ubiquitin E3 Ligase Assays, Drug Screening
Biochemical Assays
E3 Substrate Ubiquitination Assays
Gel-Based E3 Ligase Assay
Cell-Based E3 Substrate Assays
Novel E3 Ligases For PROTAC
Molecular Glue Degraders
In Vivo E3 Substrate Validation Assays
Thermal Shift Assay for E3 Ligases
Surface Plasmon Resonance for E3 Ligases
DUB Assays Screening & Profiling
Ubiquitin Flourophore Assays (Rhodamine, AMC, VME)
Ubiquitin Mass Spectrometry Proteomics
TUBE-Based Mass Spectrometry
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Ubiquitin Chain Diversity ID
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Thermal Shift Assays
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Fluorescence Polarization
Custom Solutions
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SUMO-Fusion Protein Expression & Purification
SUMOstar
Ubiquitin E3 Ligase Assays, Drug Screening
DUB Assays Screening & Profiling
Ubiquitin Mass Spectrometry Proteomics
Ligand Binding Assays
Custom Solutions
Resources
Learning Center
Ubiquitin Proteasome System
Therapeutic Relevance
Applications
FAQs
Protacs
TUBEs
SUMO
Learning Center
FAQs
Media
Press Releases
Unraveling Chain specific Ubiquitination in Cells Using Tandem Ubiquitin Binding Entities in a High Throughput Assay
Unveiling the Power of Molecular Glues at the 6th Annual Targeted Protein Degradation Summit
LifeSensors Inc. Receives $5.53 Million Funds from National Institutes of Health to Develop PROTAC Drug Discovery and Diagnosis of Alzheimer’s Disease
All Releases
Scientific Posters
HTS Screening of Poly-Ubiquitin Linkage-Specific Molecular Glues and Protein Degraders
Targeting K-RAS Molecular Glues: Kidnapping a New Ligase to Discover Novel Degraders
Accelerating PROTAC drug discovery: Establishing a relationship between ubiquitination and target protein degradation
View More
Publications & Blogs
TUBEs work in Plants!
HTS Screening of Poly-Ubiquitin Linkage-Specific Molecular Glues and Protein Degraders
Targeting K-RAS Molecular Glues: Kidnapping a New Ligase to Discover Novel Degraders
Read More Blogs
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