LYTACs
Pioneering the next generation of protein degradation therapeutics through innovative LYsosome TArgeting Chimeras
- Overview
- How LYTACs Work
- Key Components
- Therapeutic Applications
- Research Resources
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Overview
LYTACs, or LYsosome TArgeting Chimeras, are cutting-edge bifunctional molecules designed to target and degrade specific proteins outside cells by directing them to the lysosome, a cellular organelle responsible for degradation.
By harnessing the cell’s natural lysosomal degradation pathway, LYTACs can target and eliminate disease-associated proteins present outside of cells, including those involved in inflammation, cancer, and neurodegenerative disorders