Questions about a product, technology or experimental design? Give us a call 610-644-8845
Questions about a product, technology or experimental design? Give us a call 610-644-8845.

UB210T: UBE2D1, His6-SUMO

LifeSensors UB210T is a His6-SUMO tagged UBE2D1 enzyme, a 147 amino acid E2 ubiquitin-conjugating protein involved in targeting abnormal proteins for degradation.

Price range: $210.00 through $417.00

UBE2D1 is a 147 amino acid (16.6 kD) protein that mediates the degradation of abnormal proteins or proteins with short half-lives. It is a component of a Ubiquitin ligase complex including UBE2D1, SIAH1, CACYBP/SIP, SKP1, APC, and TBL1X. It also functions in E6AP-mediated ubiquitylation of p53/TP53. UBE2D1 has been shown to interact with BARD1, UBE3A, and BRCA1.

Info

Species Human
Source E. coli
Tag His6-SUMO
Molecular Weight 28,621 Da (with tag)
Quantity 0.8 nmol, 3.0 nmol
Concentration 40 µM
Formulation 50 mM Tris pH 7.5, 150 mM NaCl, 10 mM DTT, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles

Applications

  • Identify cognate E2/E3 pairs
  • Characterize upregulation/downregulation of E2 enzymes
  • Build poly-ubiquitin chains
  • Characterize ubiquitin chain specificity of E2 enzymes
  • Analyze expression of E2 enzymes

Benefits

  • Untagged (native) E2 conjugation enzyme

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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