UBE2D1 is a 147 amino acid (16.6 kD) protein that mediates the degradation of abnormal proteins or proteins with short half-lives. It is a component of a Ubiquitin ligase complex including UBE2D1, SIAH1, CACYBP/SIP, SKP1, APC, and TBL1X. It also functions in E6AP-mediated ubiquitylation of p53/TP53. UBE2D1 has been shown to interact with BARD1, UBE3A, and BRCA1.
|Molecular Weight||28,621 Da (with tag)|
|Quantity||0.8 nmol, 3.0 nmol|
|Formulation||50 mM Tris pH 7.5, 150 mM NaCl, 10 mM DTT, 10% glycerol|
|Storage||-80°C, avoid freeze/thaw cycles|