UPS Inhibitor

SI9770: MDBN

$150.00

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SKU: SI-9770-0025 Category:

Specifications

An irreversible inhibitor of p97/valosin-containing protein (VCP)/cdc48 (IC50=1.7 µM) identified in a cell-based protein degradation assay. Cell permeable.

Info

Purity >98% (HPLC), NMR (Conforms)
Quantity 25 mg
Molecular Weight 193.2 Da
Physical State Yellow powder
Solubility DMSO (50mg/ml)
CAS No. 1485-00-3
Storage 4°C, (-20°C Long term). The product can be shipped at room temperature.

Additional information

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Applications

  • Cell-based or in vitro characterization of p97/valosin-containing protein (VCP)/cdc48 function

Documents

References

[1] Chou T. F. and Deshaies R. et al. Quantitative cell-based protein degradation assays to identify and classify drugs that target the ubiquitin-proteasome system. J. Biol. Chem. 2011 286:16546