DBeQ is a cell-permeable, potent, selective and reversible inhibitor of the AAA-ATPase p97 (ATPase associated with diverse cellular activities). Ki=3.2 μM. DBeQ blocks both ubiquitin-dependent and endoplasmic reticulum-associated degradation pathways, protein clearance pathways, and activates caspases -3 and -7 inducing apoptosis.
|Purity||> 98% (TLC), NMR (Conforms)|
|Quantity||10 mg, 25 mg|
|Molecular Weight||340.4 Da|
|Physical State||Yellow powder|
|Storage||4°C, (-20°C Long term). The product can be shipped at room temperature.|