Specifications
1,10-phenanthroline (o-phenanthroline) is a chelator with a high affinity for divalent metal ions. While not specific for DUBs, it has been shown to be a potent inhibitor of JAMM-type isopeptidases through chelation of the active site Zn2+ ion. As such, o-phenanthroline is widely used when preparing cell lysates for the enrichment of proteins bearing K63-linked polyubiquitin chains which are especially sensitive to DUBs in the JAMM family.
Info
| Purity | > 99% (TLC), NMR (conforms) |
| Quantity | 0.5 mL DMSO solution, 100X |
| Molecular Weight | 198.21 Da |
| Physical State | Liquid |
| Solubility | DMSO |
| CAS No. | 5144-89-8 |
| Storage | 4°C. The Product can be shipped at room temperature. |
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