SI520: hSUMO2-AMC

SKU SI-0520-0050 Category Sumo Derivatives Chain

LifeSensors’ SI520 is a highly sensitive hSUMO2-AMC substrate for detecting SUMO protease activity at low enzyme concentrations, ideal for precise biochemical assays

$521.00

In stock

Human SUMO2-AMC is prepared via the conjugation of the C-terminus of mature human Small Ubiquitin-like Modifier (SUMO)2 to 7-amino-4-methylcoumarin (AMC), leading to quenching of the intrinsic fluorescence of AMC. Upon incubation with deSUMOylases, AMC is released and an increase in fluorescence can be measured using at 460 nm (excitation at 380 nm). The high purity of LifeSensors’ SUMO2-AMC results in improved signal to background ratios. Optimization of assay parameters and reagent requirements must be determined by the end user.

Info

Species	Human
Source	E. coli
Tag	None
Molecular Weight	10,723 Da
Quantity	50µg
Concentration	Variable
Formulation	Lyophilized powder
Storage	-80°C, avoid freeze/thaw cycles

Datasheet

Determining the activity and specificity of isopeptidases for Ub/Ubl proteins
High-Throughput Screening for modulators of dSUMOylase activity

Benefits

Highly sensitive compared to hSUMO2-AMC, hSUMO2-Rho110, and Z-RLRDGG-aminoluciferin
Allows for assaying activity at lower enzyme concentrations
Is active with SENP1, SENP2, and SENP6

Domestic Delivery
All orders placed within The United States are subject to a flat shipping fee of $80. Orders are shipped via FedEx Express Standard Overnight.

International Shipping to Canada
All orders placed within Canada are subject to a flat shipping rate of $185. Orders are shipped via FedEx Express International Priority. Shipments to Canada will only be sent from our facility on Monday, Tuesday, and Wednesday to allow for adequate delivery time.

International Worldwide
All orders to be delivered to Europe, Asia, Australia and South America are subject to a flat shipping fee of $325. Orders are shipped via FedEx Express International Priority.

Customers can also use their own shipping account for deliveries if preferred. Please include the Fedex or DHL shipping account number when the order is placed or reach out to customerservice@lifesensors.com for more information.

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SI520: hSUMO2-AMC

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