SI219: Ubiquitin-K48R K63R

$179.00

In stock

SKU: SI-0219-1000 Category: Tag:

Specifications

Recombinant ubiquitin having arginine substituted for lysine at positions 48 and 63. Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation.  Additional ubiquitin moieties can be subsequently conjugated to this initial ubiquitin. Utilizing any one (of seven) lysine residues on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 8,620 Da
Quantity 1 mg
Concentration Variable
Formulation 20 mM Tris pH 7.5, 150 mM NaCl, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles

Additional information

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Applications

  • Investigation of E1-E2-E3 mediated ubiquitin ligation.
  • Investigation of DUB linkage specificity.

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