SI217: Ubiquitin-K48R


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SKU: SI-0217-1000 Category:


Recombinant ubiquitin having a single substitution of arginine for lysine at position 48. Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can subsequently conjugated to this initial ubiquitin, utilizing any one (of seven) lysine residues on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation.


Species Human
Source E. coli
Tag None
Molecular Weight  8,592 Da
Quantity 1 mg
Concentration Variable
Formulation PBS with 10% glycerol
Storage -80°C, avoid freeze/thaw cycles

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  • Investigation of E1-E2-E3 mediated ubiquitin ligation.
  • Investigation of DUB linkage specificity.