SI213: Ubiquitin-K11R

$179.00

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SKU: SI-0213-1000 Category:

Specifications

Recombinant ubiquitin having a single substitution of arginine for lysine at position 11. Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to amine groups of lysine residue on target proteins. This conjunction is referred to as monoubiquitylation. Additional ubiquitin moieties can be subsequently conjugated to this initial ubiquitin, utilizing any one (of seven) lysine residues on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 8,592 Da
Quantity 1 mg
Concentration Variable
Formulation 20 mM Tris pH 7.5, 150 mM NaCl, 10% glycerol
Storage -80°C, avoid freeze/thaw cycles

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  • Investigation of E1-E2-E3 mediated ubiquitin ligation.
  • Investigation of DUB linkage specificity.