SI1104: K11-Linked Tetra-Ubiquitin

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Specifications

Increasingly, researchers are focusing on the role of poly-ubiquitin chains linked through K11. This post-translational modification has been linked to ERAD as a signal for proteasomal degradation. In addition, K11-linked chains appear to play an important role in cell cycle signaling, as they are associated with the anaphase promoting complex (APC) of ubiqiutylation machinery. These tetra-ubiquitin chains are generated through the enzymatic linkage of wild-type ubiquitin through lysine 11 and purified to 95% homogenity by ion exchange chromatography.

Info

Species Human
Source E. coli
Tag None
Molecular Weight 34,205.4 Da
Quantity 25 µg
Concentration Variable
Formulation Phosphate Buffered Saline pH 7.4
Storage -80°C, avoid freeze/thaw cycles

 

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Applications

  • Investigation of DUB linkage specificity.

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