Specifications
Increasingly, researchers are focusing on the role of poly-ubiquitin chains linked through K11. This post-translational modification has been linked to ERAD as a signal for proteasomal degradation. In addition, K11-linked chains appear to play an important role in cell cycle signaling, as they are associated with the anaphase promoting complex (APC) of ubiqiutylation machinery. These tetra-ubiquitin chains are generated through the enzymatic linkage of wild-type ubiquitin through lysine 11 and purified to 95% homogenity by ion exchange chromatography.
Info
Species | Human |
Source | E. coli |
Tag | None |
Molecular Weight | 34,205.4 Da |
Quantity | 25 µg |
Concentration | Variable |
Formulation | Phosphate Buffered Saline pH 7.4 |
Storage | -80°C, avoid freeze/thaw cycles |
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