PR1001 Ub-CHOP-Reporter (Reporter System) 220 ul (4uM)

PR1104: NEDD8-CHOP2 Reporter System

$975.00

In stock

Specifications

The NEDD8-CHOP-Reporter DeNEDDylation Assay Kit consists of NEDD8 fused to a reporter enzyme and the reporter enzyme substrate. When fused to NEDD8, the reporter is rendered catalytically inactive. Following cleavage of the NEDD8-reporter system by isopeptidase activity, the free (and now active) reporter enzyme subsequently acts upon its substrate. Thus, in this coupled assay, the signal generated by cleavage of the reporter enzyme’s substrate is a quantitative measure of isopeptidase activity. This product is protected by one or more US or Foreign patents. Please read the Limited Use Label License to learn more. By purchasing this product, the purchaser agrees to comply with these terms.

Contents

  • NEDD8-CHOP2-Reporter (Reporter System): 1 x 375 μL (4 μM)
  • Den1 (Control Isopeptidase): 2 x 10 μL (2 μM)
  • Reporter Substrate 2: 1 x 30 μL (25 μM)
  • Control Fluorophore 2: 1 x 20 μL (1 mM)

 

Info

Storage -80° C, avoid freeze/thaw cycles

Additional information

SKU

Reviews

There are no reviews yet.

Be the first to review “PR1104: NEDD8-CHOP2 Reporter System”
  • Demostration of novel DeNEDDylating activity
  • High throughput screening (HTS) for either agonists or antagonists of DeNEDDylating activity