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UM101-200µg Anti-Ub Tube1, GST

UM312: TUBE 2 (HRP)

LifeSensors UM312 (TUBE 2 HRP) is a high-affinity polyubiquitin detection tool, enabling sensitive, selective pull-down and analysis of ubiquitylated proteins for proteomics and drug discovery.

$648.00

SKU UM-0312-0050 Categories Pan-Selective TUBEs, TUBEs for Detection, TUBEs: Ubiquitin Affinity Matrix Tags Pan-selective, Pull down, Tandem Ubiquitin Binding entities

In stock

Product Advantages

Applications

Detection of polyubiquitylated proteins by ligand blotting (use a 1:1000 to 1:5000 dilution for most applications)

In situ labeling for detection of polyubiquitin by histochemistry

Based on protein domains known to possess an affinity for ubiquitin, Tandem Ubiquitin Binding Entities (TUBEs) have been developed for the isolation and identification of ubiquitylated proteins. TUBEs display up to a 1000-fold increase in affinity for polyubiquitin moieties over the single ubiquitin binding associated domain (UBA). In addition, TUBEs display a protective effect on polyubiquitinated proteins, allowing for detection at relatively low abundance. These properties effectively “capture” proteins in their polyubiquitylated state. We have developed the HRP-TUBE 2 for quick and easy detection of polyubiquitin and polyubiquitinated substrates. This product is protected by one or more US or Foreign patents. Please read the Limited Use Label License to learn more. By purchasing this product, the purchaser agrees to comply with these terms.

Info

Tag	HRP
Molecular Weight	56.5 kDa
Physical State	Liquid
Quantity	50 µg
Concentration	Variable
Storage	-80°C, avoid freeze/thaw cycles

Datasheet

Datasheet

Applications

Detection of polyubiquitylated proteins by ligand blotting (use a 1:1000 to 1:5000 dilution for most applications)

In situ labeling for detection of polyubiquitin by histochemistry

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