PC1008: LS E3 1017

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SKU: PC-1008 Categories: ,

Specifications

LS E3 1017 is a derivative of thalidomide (Cat.No. PC-1006) and is commonly used as a precursor to PROTACs that hijack cereblon as the E3 ubiquitin ligase component. It is supplied with a carboxylic acid functional handle at a position known not to significantly affect binding to cereblon, for ready conjugation to a linker/target protein ligand.

Info

Purity >98%
Quantity 5 mg, 10 mg, 25 mg
Molecular Weight 332.26 g/mol
Physical State Lyophilized off white solid
Solubility 30 mg/mL in DMSO
CAS No. 1061605-21-7
Storage Room Temperature

Additional information

Weight

5 mg, 10 mg, 25 mg

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LS E3 1017 is a functionalized cereblon ligand for PROTACs