Specifications
A pan-specific ubiquitin & ubiquitin-like isopeptidase inhibitor. Inhibits USP2, USP7, and SENP2 with EC50 values of 45 ± 4 μM, 37 ± 1 μM, and 9.8 ± 1.8 μM, respectively. Does not affect proteasome proteolytic activity. Induces apoptosis via a Bcl-2-dependent but apoptosome-independent mitochondrial pathway. Cell permeable.
Info
| Purity | >98% (HPLC); NMR (Conforms) |
| Quantity | 10 mg, 50 mg |
| Molecular Weight | 339.9 Da |
| Physical State | Yellow Powder |
| Solubility | DMSO (8 mg/mL) |
| CAS No. | 157654-67-6 |
| Storage | 4°C, (-20°C Long term). Store solutions at -20°C for up to 1 month. The product can be shipped at room temperature. |
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