USP7 (HAUSP) was originally identified by its binding activity to a herpes viral protein, ICPO. USP7 plays a key role in regulating the ubiquitination and the stability of the RING-finger E3 ligase Mdm2 (and its human homolog Hdm2). Additional targets of USP7 have been identified including the forkhead transcription factor, FOXO44.
|Molecular Weight||135 kDa|
|Storage||-80°C, avoid freeze/thaw cycles|