USP14 is a ubiquitin specific protease that associates with the proteasome. This association with the proteasome has been shown to enhance the enzymatic activity of the proteasome. Recent studies have demonstrated that the expression of USP14 in certain cancers correlates with metastasis. Using a chemical probe, it has been shown that USP14 can interact with ISG15, a ubiquitin-like protein.
|Storage||-20°C, Avoid freeze/thaw cycles|