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LifeSensors

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18
Jun
Protein Profiles: α-Synuclein

Protein Profiles: α-Synuclein

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α-SynucleinPDB ID: 1XQ8α-Synuclein is mainly found in the brain and is present at the presynaptic terminal of neurons. Although its function in a healthy brain is currently unknown, α-Synuclein is b...


06
Jul
Protein Profiles: PINK1

Protein Profiles: PINK1

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PINK1PDB ID: 50ATPTEN induced putative kinase 1 (PINK1) is important in the role of mitophagy, once it accumulates on the outer membrane of a damaged mitochondria, it summons PARKIN to begin the pro...


18
Jun
Protein Profiles: β-Amyloid

Protein Profiles: β-Amyloid

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β-AmyloidPDB ID: 38KCAmyloid precursor proteins (APP), present in the fatty membrane of neuronal cells, undergo a series of enzymatic cleavages to create smaller proteins known as β-Amyloid. Sometim...


19
Jun
Protein Profiles: Paris (ZNF746)

Protein Profiles: Paris (ZNF746)

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Source: https://doi.org/10.1016/j.cell.2011.02.010PARIS (ZNF746)Recently found to have drastic implications in Parkinson’s, researchers have shown PARIS to be a key regulating factor of neuronal...


06
Jul
Protein Profiles: Parkin

Protein Profiles: Parkin

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ParkinPDB ID: 5C1ZParkin is an E3 ligase, which ubiquitinylates proteins for degradation within neurons, and is primarily associated with mitophagy. By tagging damaged proteins with ubiquitin, the n...


18
Jun
Protein Profiles: Tau Proteins

Protein Profiles: Tau Proteins

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Tau ProteinsPDB ID: 5D2VWithin healthy neurons, tau proteins are responsible for stabilizing microtubules within the cell. Unfortunately, in instances associated with neurodegenerative disease these...


31
May
LifeSensors to Attend the 2018 BIO International Convention

LifeSensors to Attend the 2018 BIO International Convention

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LifeSensors is a leader in Ubiquitin Proteasome System (UPS) drug discovery technologies and SUMO Platform for Difficult to Express Proteins. We are pleased to inform you that members of our team will...


29
May
LifeSensors Announces New Distribution Agreement with AmyJet in China

LifeSensors Announces New Distribution Agreement with AmyJet in China

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Press Release May 29, 2018 271 Great Valley Parkway Malvern, PA 19355LifeSensors Announces New Distribution Agreement with AmyJet in ChinaLifeSensors Inc, a Biotech and Drug Discovery Comp...


23
May
LifeSensors is Proud to Sponsor the 2018 Fusion Ubiquitin Conference in Nassau, Bahamas

LifeSensors is Proud to Sponsor the 2018 Fusion Ubiquitin Conference in Nassau, Bahamas

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LifeSensors is Proud to Sponsor the 2018 Fusion Ubiquitin Conference in Nassau, BahamasIt is with great pride that LifeSensors announces its sponsorship of the 2018 Fusion Conference The Ubiquitin Sys...


22
May
Hope for the Future of Alzheimer's Research

Hope for the Future of Alzheimer's Research

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HOPE FOR THE FUTURE OF ALZHEIMER’S RESEARCHCurrent Paradigms and Innovative ResearchDear Colleagues,Alzheimer's and Parkinson's diseases are the silent killers. Despite a massive investment, the failu...


17
May
A New Generation of TUBEs

A New Generation of TUBEs

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A New Generation of TUBEsDear Colleagues,Deciphering the Ubiquitin Code is the first step in utilizing the Ubiquitin Proteasome System (UPS) to drug the so-called undruggable targets.  LifeSensor...


09
May
Ubiquitin: Hope for the Future of Alzheimer's Research

Ubiquitin: Hope for the Future of Alzheimer's Research

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Ubiquitin: Hope for the Future of Alzheimer’s Researchby: Mark Tingey and Peter Foote    Uncle Walt stared at us, not recognizing us or remembering our names.  His eyes, which were onc...


09
May
We have developed a new website for customers to follow our innovations and the future of medicine by exploring the ubiquitin and SUMO pathway

We have developed a new website for customers to follow our innovations and the future of medicine by exploring the ubiquitin and SUMO pathway

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We have developed a new Website for customers to follow our innovations and the future of medicine by exploring the ubiquitin and SUMO pathway Check out our new featuresLifeSensors has ...


08
May
Deciphering the Ubiquitin Code with Poly-Ubiquitin Chain Selective Affinity Matrices

Deciphering the Ubiquitin Code with Poly-Ubiquitin Chain Selective Affinity Matrices

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Deciphering the Ubiquitin Code with Poly-Ubiquitin Chain Selective Affinity MatricesLifeSensors recently presented the work of Rajesh Singh, Cari Sagum, Jianji Chen, Apurva Chaturvedi, Peter Foote, an...


27
Apr
Ubiquitin code: Accelerating the discovery of poly-ubiquitylated proteins by novel chain-selective affinity matrices

Ubiquitin code: Accelerating the discovery of poly-ubiquitylated proteins by novel chain-selective affinity matrices

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  • 852 Views
Ubiquitin code: Accelerating the discovery of poly-ubiquitylated proteins by novel chain-selective affinity matricesLifeSensors' Scientists Apurva Chaturvedi, Peter Foote, Dominic Vasturia, and Rajesh...


09
May
Establishing Ubiquitylation Patterns in Cells: Efficient Monitoring of Oncogenic Ubiquitylation Activity

Establishing Ubiquitylation Patterns in Cells: Efficient Monitoring of Oncogenic Ubiquitylation Activity

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Establishing Ubiquitylation Patterns in Cells: Efficient Monitoring of Oncogenic Ubiquitylation Activity...