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LifeSensors

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SI9619-5X5MG PR-619

$465.00
  • Product Code: SI9619-5X5MG PR-619
  • Availability: In Stock

PR-619 is a non-selective, reversible inhibitor of deubiquitinases/deubiquitylases (DUBs) and ubiquitin-like isopeptidases.  PR-619 inhibits many deubiquitinating enzymes in the 5-20 µM range.  Additionally, PR-619 is cell-permeable and treatment of cells results in the accumulation of both ubiquitin and sumo-conjugated proteins.

Info
Purity   ≥ 95% (RP-HPLC)
Molecular weight   223.28 Da
Physical state   Dry powder
Solubility   5 mg/mL in DMSO
Storage   4 °C, with long term storage down to -25°C. Product can be shipped at room temperature. 



Applications
  • Non-specific inhibition of isopeptidases
  • Cell biology
  • Preparation of cell/tissue lysates
  • Drug discovery
  • Benefits: cell-permeable


Documents

Thumb File information
PR-619_Application_note_.pdf 83.19KB 0
SI-9619 datasheet.pdf 65.18KB 0
PR619_white_paper.pdf 309.77KB 0

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