Ubiquitin Proteasome System

The ubiquitin proteasome system degrades damaged proteins so the components can be reused. This system is vitally important for proper cell function and has been tied to diseases such as neurodegeneration and cancer.

E3 Ligases

The E3 ligase ubiquitinates the target protein and contributes selectivity and specificity to the ubiquitin proteasome system.

Our Ligase Assays

LifeSensors offers an ELISA assay as well as a TR-FRET assay to monitor E3 ligase activity. Explore our options and let us help you decide the best experiment for your specific question.

Applications of E3 Assays

Our methods allow you to identify the optimal E2/E3 pair, identify poly-ubiquitin linkage types, and screen compounds against E3 ligases.

The LifeSensors Advantage

We are committed to helping you answer the important research questions by offering expert, professional service and an efficient workflow.

Contact us to learn more about this service.