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Feb 13
Love9

LifeSensors is Proud to Sponsor the “Druggability of the Ubiquitin System” Conference in Lisbon, Portugal

By admin News No Comments

LifeSensors has spent years supporting the drug discovery efforts in Ubiquitin Proteasome System (UPS) research. We are excited to see this growing area of research gain more attention through conferences…

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Nov 08
Love7

Proteomics Discovery of Ubiquitylated Biomarkers for Neurodegenerative Disease

By admin Publications No Comments
  ABSTRACT Ubiquitin-Proteasome system (UPS), along with chaperone mediated-autophagy (CMA) and macroautophagy, constitutes the protein quality control system of the cell. The failure of these systems is particularly difficult to...
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Nov 06
Love5

PROTAC Method of Action Presentation

By admin Publications No Comments
SEE THE LIFESENSORS PRESENTATION ON NOVEL PROTAC ASSAYS HERE. PLEASE CONTACT US FOR MORE INFORMATION ON THIS EXCITING TECHNOLOGY- BD@LIFESENSORS.COM
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Aug 10
Love1

PARKINSON’S DISEASE: BIOMARKERS OF EARLY DISCOVERY

By admin Education No Comments

By: Mark Tingey, Katelyn Roberts, and Meredith Paterson Parkinson’s disease is often referred to as a silent disease. It often begins in very innocuous ways, small ticks and behaviors that…

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Jul 26
Love6

LifeSensors to Sponsor Discovery on Target

By admin Press Releases No Comments

LIFESENSORS TO SPONSOR DISCOVERY ON TARGET To help further scientific advancement in the field of ubiquitin, LifeSensors has partnered with CHI to assist with their Discovery on Target conference this…

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Jul 10
Love5

New Developments in Ubiquitomics: Discovery of poly-ubiquitylated proteins by novel chain-selective TUBEs

By admin Publications No Comments
LifeSensors Scientists Apurva Chaturvedi, Peter Foote, Li Liang, Dominic Vasturia, and Rajesh Singh recently presented research at FASEB in SnowMass, Colorado. A downloadable PDF of this poster can be found...
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Jul 10
Love6

Protein Profiles: UCHL1

By admin Education No Comments

UCHL1 The protein encoded by UCHL1 (Ubiquitin C-Terminal Hydrolase L1) is a thiol protease belonging to the C12 family of peptidases that hydrolyze peptide bonds at the C-terminal glycine of…

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Jul 10
Love6

Protein Profiles: USP14

By admin Education No Comments

USP14 USP14 is a ubiquitin specific protease that associates with the proteasome. This association with the proteasome has been shown to enhance the enzymatic activity of the proteasome. Recent studies…

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Jul 10
Love6

Protein Profiles: USP8

By admin Education No Comments

USP8 USP8 is associated with endosomal trafficking, it is not clear that this isopeptidase is involved in the commitment to lysosomal sorting. Additional research has shown that USP8 plays a…

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Jul 10
Love6

Protein Profiles: E6-AP

By admin Education No Comments

E6-AP E6-AP (E6-associated protein) is an E3 (ubiquitin protein ligase) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E2 enzymes. It is a…

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PROTAC IS A REGISTERED TRADEMARK OF ARVINAS OPERATIONS, INC., AND IS USED UNDER LICENSE.

LIFESENSORS

Our business development team works with customers to develop simple and cost effective work plans. We facilitate a smooth transfer of our technology, offering transfer and licensing terms that fit the needs of the client’s laboratory and organization. Our team is dedicated to providing state-of-the-art products to help put your research and development efforts into the forefront. We’ve developed non-traditional approaches and scalable discounts to bring our technology to your lab.

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LifeSensors Inc.

    Menu
    • Home
    • Our Technologies
      • PROTAC & DUBTAC Drug Discovery
      • Tandem Ubiquitin Binding Entities (TUBEs)
      • Ubiquitin and Ubiquitin Chains
      • SUMO Technology and Difficult to Express Proteins
        • Polypeptide Manufacturing
        • Therapeutic Proteins, Dramatic Enhancement
        • Nanobodies and Single Chain Antibodies
        • Vaccine Manufacturing with SUMO
        • Gene Therapy: SUMO to the Rescue
      • Molecular Glue Degraders
      • Neurodegeneration
    • R&D Services
      • PROTACs & Molecular Glues
        • PROTAC® Degradation Assays
        • PROTAC® Ubiquitination Assays
        • Target Exploration and Validation
        • Novel E3 Ligases for PROTAC ®
        • PROTAC Ternary Complex Assays
        • PROTAC for Cancer
        • PROTAC for Neuroscience
      • E3 Ubiquitin Ligases Profiling & Screening
        • Thermal Shift Assay for E3 Ligases
        • Surface Plasmon Resonance for E3 Ligases
        • Biochemical Assays (High Throughput Screening)
        • E3 TR-FRET Assay
        • E3 ELISA Assay
        • Cellular Assays (Hit Validation)
        • UbiQuant ELISA (Cellular)
        • UbiTest Substrate Validation
      • DUB Assays, Screening & Profiling
        • Ubiquitin Fluorophore Assay (Rhodamine, AMC, VME)
        • Physiological DUB Assays
        • Di-Ubiquitin IQF Assay (Patented)
        • CHOP Assay-  Ubiquitin, SUMO, ISG15 & NEDD8 (Patented)
      • SUMO-Tag Protein Expression & Purification
        • SUMOpro
        • Bacterial 
        • Mammalian
        • SUMOstar 
        • Advanced Therapeutic Applications
        • Mammalian
      • Mass Spectrometry Proteomics
        • TUBE-Based Mass Spectrometry
        • E3 Ligase Substrate ID
        • DUB Substrate ID
        • Whole Cell Proteomics
        • Target Substrate Lysine Ubiquitination ID
        • Ubiquitin Chain Diversity ID
      • Ligand Binding Assays
        • Thermal Shift Assays 
        • Surface Plasmon Resonance
        • Fluorescence Polarization
    • Products
      • PROTAC Tools
        • PROTAC Ubiquitin Assays
        • PROTAC Ubiquitin Plates
        • In Vitro Assay in PROTAC
        • Small Molecule Modulators and PROTACs
        • Autophagy Modulators
        • UPP Inhibitor Library
        • E1-E2-E3 Inhibitors
        • DUB inhibitors
        • Proteasome Inhibitors
        • p97 Inhibitors
      • TUBEs: Ubiquitin Affinity Matrix
        • Pan-Selective TUBEs
        • K48 TUBEs HF
        • K63 TUBEs
        • Linear- M1 TUBE1
        • TUBEs for Detection
        • Magnetic TUBEs
        • Antibodies
        • Ubiquitin Antibodies
        • DUB and Ubiquitin Like Isopeptidase Antibodies
        • SUMO Antibodies
      • Ubiquitin Ligases and Enzymes
        • E1 Ubiquitin Activating Enzymes
        • E2 Ubiquitin Conjugating Enzymes
        • E3 Ubiquitin Ligases
        • Proteasomal Research Tools
        • Kits and Plates
        • E1-E2-E3 Assays
        • High-throughput Plates
        • UbiTest
        • UbiQuant
      • Deubiquitinating enzymes (DUBs)
        • USP Family of DUBs
        • UCH Family of DUBs
        • OTU Family of DUBs
        • JAMM Family of DUBs
        • MJD Family of DUBs
        • Viral and Bacterial DUBs
        • Deneddylases
        • DeSUMOylases
      • SUMO Protein Expression System
        • Bacteria
        • Mammalian cells
        • Insect cells
        • Yeast
        • SUMO Protease Enzymes
        • SUMO Protease 1
        • SUMO Protease 2
        • SUMOstar Protease
      • Ubiquitin Chains and Derivatives
        • Ubiquitin and Neuro-degeneration
        • Ubiquitin Chains
        • Ubiquitin K to R mutants
        • Ubiquitin Derivatives
        • Sumo Derivatives Chain
        • Isotopically-Labeled ubiquitin
        • CHOP2 Reporter Assays
        • IQF Diubiquitins
    • Resources
      • Discussion Forum
      • FAQs
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