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PC1004 Lenalidomide 1g

  • Product Code: PC1004 Lenalidomide 1g
  • Availability: Contact us for lead time

Thalidomide analog. Immune modulatory drug and cereblon binding compound. Induces ubiquitination and degradation of casein kinase (CK) 1α by the E3 ubiquitin ligase CRL4CRBN. Also TNF-α inhibitor and angiogenesis inhibitor.


Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase

Product Information

Purity:                            >97% 

MW:                              259.26

Formula:                      C13H13N3O3

CAS Number                191732-72-6

Physical State:       Lyophilized white to yellow solid

Quantity:                      1g; 5g

Solubility:                      25 mg/mL in DMSO

Storage:                      Room Temperature



1.    Petzold et al (2016) Structural basis of lenalidomide-induced CK1a degradation by the CRL4(CRBN) ubiquitin ligase. Nature 532 127 PMID: 26909574

2.    Krönke et al (2015) Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS. Nature 523183 PMID: 26131937

Thumb File information
Lenalidomide D atasheet.pdf 165.91KB 0

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