The Ubiquitin-Proteasome System: An Overview The Ubiquitin-Proteasome system (UPS) is a highly complex, temporally…
Myra ZerrMarch 1, 2021
Our Services
PROTAC® Drug Discovery
PROTAC compounds, plate-based in vitro and cellular HTS assays
Mass Spec Ubiquitin Proteomics
Global substrate ID, TUBE-based affinity matrices, Tandem mass spec, and custom assays
E3 Ligase Screening & Profiling
Plate-based assays, best E2 identification, ubiquitin chain identification, compound library screening, custom assays
DUB Screening & Profiling
Plate-based assays, compound library screening, ubiquitin chain selectivity, custom assays
Protein Expression & Purification
SUMO-tag system for both prokaryotic and eukaryotic cells to maximize protein expression
Biomarker Assay Development
Assay development and biomarker identification for drug optimization
Biophysical Assays
Surface Plasmon Resonance (SPR); Thermal Shift Assay (TSA); Protein-Protein interactions; Protein-ligand interactions
Our Products
TUBEs: Ubiquitin Affinity Matrix
Pan-selective TUBEs, SUMO traps, K48-, K63- and linear M1 selective TUBEs
Kits and Plates
PROTAC® Assay Plate; UbiTest: substrate ubiquitylation; UbiQuant/S: high-throughput ubiquitylation
Protein Expression Systems
SUMO/SUMOpro/SUMOstar maximizes solubility and yield of your protein in any host
Ubiquitins and Chains
Ubiquitin fluorescent probes, lysine mutants, and polyubiquitin chains, Diubiquitin IQFs, CHOP ubiquitin reporter
Ubiquitin Pathway Enzymes
E1 and E2 enzymes, E3 ligases, DUBs,
Proteasomal tools
Antibodies & Inhibitors
Top-rated VU-1 antibody, ubiquitin antibodies, Ubiquitin pathway inhibitors and antibodies
November is a month dedicated to the awareness of Alzheimer’s Disease, an age-related illness of…
Myra ZerrNovember 23, 2020
DTE proteins, or ‘difficult-to-express’ proteins are a common hurdle for researchers in the lab. Due…
Myra ZerrJuly 27, 2020
LifeSensors is happy to say we’re growing! We’ve always been one to say more the…
Myra ZerrJune 26, 2020